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About the statement & hepatitis C
Introduction
Epidemiology
Tables
Figures
abbreviations
References
Methodology
Models of care In Australia
Introduction
Tertiary centre-led
GPs in Primary Care
Nurse led
Custodial settings
People who inject drugs (PWID) and opioid substitution centres (OTS)
Rural and remote settings
Aboriginal and Torres Strait Island Peoples
Migrant populations
People with mental health problems
Recommendations: Models of care
References
Pre-treatment assessment
Screening and Diagnosis
Screening and diagnosis recommendations
Introduction to pre-treatment assessment
Perform Virological evaluation
Evaluate for presence of Cirrhosis
Consider whether there are coexisting diseases present
Drug-drug interactions
Adherence to treatment
Recommendations: Pre-treatment assessment
References
Treatment for chronic HCV
Goal of treatment
Indications for treatment
DAAs
Pan-genotypic regimens for chronic infection with genotypes 1–6 HCV
Regimens for chronic infection Gt 1 HCV
Regimens for chronic infection Gt 2 HCV
Regimens for chronic infection Gt 3 HCV
Regimens for chronic infection Gt 4, 5 & 6 HCV
Peginterferon-alfa-related adverse events
Drug-drug interactions
Pregnancy, breastfeeding, and children
DAAs and drug resistance
Salvage therapy
Recommendations: Treatment for chronic HCV
References
Monitoring and follow-up
On treatment monitoring
Consensus recommendations
Post-treatment follow-up
Recommendations: Monitoring and follow-up
References
Special Populations
Recommendations: Treatment of decompensated liver disease
Post liver transplantation
Recommendations: Treatment post liver transplantation
HCV/ HIV co-infection
Recommendations: HIV/HCV co-infection
HCV/ HBV co-infection
Treatment of HCV in people with renal impairment
Recommendations: HCV/HBV co-infection
Renal impairment
Recommendations: Treatment for HCV and renal impairment
Acute HCV infection
Recommendations: Treatment for acute HCV
References
Direct-acting antiviral therapy and risk of hepatocellular carcinoma in people with cirrhosis
Consensus recommendations
Models of Care
Screening and Diagnosis
Pre-treatment assessment
Treatment for chronic hepatitis C
On-treatment monitoring
Post-treatment follow-up
Decompensated liver disease
HCV post liver transplantation
HCV/ HIV co-infection
HCV/ HBV coinfection
Renal impairment
Acute HCV infection
Contributors:
Pre-treatment Assessment
Screening and diagnosis
Screening and diagnosis recommendations
Introduction
Perform Virological evaluation
Consider whether there are coexisting diseases present
Evaluate for presence of Cirrhosis
Drug-drug interactions
Adherence to treatment
Recommendations: Pre-treatment assessment
References
Treatment for chronic HCV
Goal of treatment
Indications for treatment
DAAs
Regimens for chronic infection Gt 1 HCV
Regimens for chronic infection Gt 2 HCV
Regimens for chronic infection Gt 3 HCV
Regimens for chronic infection Gt 4, 5 &6 HCV
Drug-drug interactions
Pregnancy, breast feeding,and children
DAAs and drug resistance
Salvage therapy
Recommendations: for the treatment of chronic HCV
References
Monitoring and follow-up
On treatment monitoring
Recommendations: On-treatment monitoring
Post treatment follow-up
Confirm SVR12
Long term management of liver disease
Recommendations: Post-treatment follow-up
References
Special Populations
Treatment of decompensated liver disease
Recommendations: Treatment of decompensated liver disease
Post liver transplantation
Recommendations: Treatment post liver transplantation
HCV/ HIV co-infection
Recommendations: HCV/HIV co-infection
HCV/ HBV co-infection
Recommendations: HCV/HBV co-infection
Renal impairment
Recommendations: Treatment for renal impairment
Acute HCV infection
Recommendations: Treatment for acute HCV infection
References
About the statement & hepatitis C
Introduction
Epidemiology
Tables
Figures
abbreviations
References
Methodology
Models of care In Australia
Introduction
Tertiary centre-led
GPs in Primary Care
Nurse led
Custodial settings
People who inject drugs (PWID) and opioid substitution centres (OTS)
Rural and remote settings
Aboriginal and Torres Strait Island Peoples
Migrant populations
People with mental health problems
Recommendations: Models of care
References
Pre-treatment assessment
Screening and Diagnosis
Screening and diagnosis recommendations
Introduction to pre-treatment assessment
Perform Virological evaluation
Evaluate for presence of Cirrhosis
Consider whether there are coexisting diseases present
Drug-drug interactions
Adherence to treatment
Recommendations: Pre-treatment assessment
References
Treatment for chronic HCV
Goal of treatment
Indications for treatment
DAAs
Pan-genotypic regimens for chronic infection with genotypes 1–6 HCV
Regimens for chronic infection Gt 1 HCV
Regimens for chronic infection Gt 2 HCV
Regimens for chronic infection Gt 3 HCV
Regimens for chronic infection Gt 4, 5 & 6 HCV
Peginterferon-alfa-related adverse events
Drug-drug interactions
Pregnancy, breastfeeding, and children
DAAs and drug resistance
Salvage therapy
Recommendations: Treatment for chronic HCV
References
Monitoring and follow-up
On treatment monitoring
Consensus recommendations
Post-treatment follow-up
Recommendations: Monitoring and follow-up
References
Special Populations
Recommendations: Treatment of decompensated liver disease
Post liver transplantation
Recommendations: Treatment post liver transplantation
HCV/ HIV co-infection
Recommendations: HIV/HCV co-infection
HCV/ HBV co-infection
Treatment of HCV in people with renal impairment
Recommendations: HCV/HBV co-infection
Renal impairment
Recommendations: Treatment for HCV and renal impairment
Acute HCV infection
Recommendations: Treatment for acute HCV
References
Direct-acting antiviral therapy and risk of hepatocellular carcinoma in people with cirrhosis
Consensus recommendations
Models of Care
Screening and Diagnosis
Pre-treatment assessment
Treatment for chronic hepatitis C
On-treatment monitoring
Post-treatment follow-up
Decompensated liver disease
HCV post liver transplantation
HCV/ HIV co-infection
HCV/ HBV coinfection
Renal impairment
Acute HCV infection